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KMID : 1023320080120010015
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Korean Journal of Exercise Nutrition
2008 Volume.12 No. 1 p.15 ~ p.20
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Effect of Acute Exercise on Fatty Acid Transporter mRNAs Levels for Expression in Skeletal Muscle
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Lim Ki-Won
Cheon Woo-Kwang
Suh Hea-Jung
Tomohiro Tamura
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Abstract
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Purpose: The purpose of this study was to investigate the effect of acute exercise training on FAT (fat acid transporter), FATP (fat acid transcript protein), FABP (fat acid binding protein) of skeletal muscle in rat.
Methods: Sixty-four Male Sprague-Dawley rats (5 wk) were divided into control (CON) and exercise (EX), recovery group (EXRest). The rats of CON were sacrificed at 0 min, 60 min and 24 hr. The rats of EX were sacrificed at 0 min, 15 min, 30 min and 60 min during treadmill running exercise. The rats of EX-Rest were sacrificed at 0min, 1 hr, 3 hr, 6 hr and 24 hr of recovery from 1 hr treadmill running exercise. Analysis; The measured data of fat acid transporters mRNA were analyzed with Indepent Sample t-test and Paired Samples t-test using SPSS statistics (version 11.5).
Results: The acute exercise effect on FAT mRNA expression were significantly (p < 0.05) increased at 60 min during exercise. FATP mRNA expression were significantly (p < 0.05) increased at 30 min and 60 min during exercise. also FABP mRNA expression were significantly (p < 0.05) increased at 1 hr after exercise.
Conclusion: This study acute exercise was induce the expression of FAT, FATP and FABP mRNA in rat muscle.
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KEYWORD
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FAT/CD36, FATP, FABP, skeletal muscle, acute exercise, fat oxidation
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